Hodgkin’s Lymphoma: An Environmental Scan

Table of Contents Controlled Amino Acid Therapy

Since the late 1940’s and certainly into the 1960’s, the relationship between chemical reactions within the body and the growth of cancer cells has been an area of interest for a select group of researchers. Furthermore, understanding the effect of nutritional components as initiators or catalysts in such reactions is the focus of current clinical investigations. At the National Cancer Institute and the University of Chicago, two physicians, Dr. Rabinowitz and Dr. Lorincz are investigating controlled amino acid therapy (CAAT) and the biochemical effect of such therapy on altering or impairing the DNA synthesis of cancer cells. The CAAT therapy creates a deficiency in the amino-acid availability within the body, virtually eliminating all other sources of protein and reduces carbohydrates, thus inhibiting, even stopping the growth of cancers cells by restricting the availability of crucial protein components a cancer cell must have in order to self-replicate. Additionally, it is well known that cancer cells use glucose almost exclusively to feed on, thus a diet which dramatically reduces carbohydrates sets up a deprivation in the amount of energy available to the cancer cell. Interestingly, the science behind CAAT is the very same approach used in current chemotherapy treatments, the inhibition of DNA and protein synthesis, and interferes with signal transduction receptors on the cellular membrane of cancer cells, thereby impeding their growth (Haddad 2009).